Innovative Research Lab
Publications
2023
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Cui, M., Xiaoyu Chen, Luo, X., Zhou, Z., Chen, Z., Zhou, Z., Zhou, X., Zou, H., Xu, T., Wang, S. & Yang, M., “Dually stimulative single-chain polymeric nano lock with dynamic ligands for sensitive detection of circulating tumor cells.” Biosensors & bioelectronics, 2022, 217, 114692.
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Liu, Y., Xiao, M., Xu, N., Yang, M. & Yi, C. “Point-of-need quantitation of 2,4-dichlorophenoxyacetic acid using a ratiometric fluorescent nanoprobe and a smartphone-based sensing system.” Sensors and Actuators B: Chemical, 2022. 367. 13208
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Wang, Q., Yang, Q., Liu, C., Wang, G., Song, H., Shang, G., Peng, R., Qu, X., Liu, S., Cui, Y., Wang, P., Xu, W., Zhao, X., Qi, J., Yang, M. & Gao, G. F. “Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.” Proceedings of the National Academy of Sciences of the United States of America, 2022, 119, 4, e2118590119.
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Yang, Z., Zhou, Z., Si, T., Zhou, Z., Zhou, L., Chin, Y. R., Zhang, L., Guan, X. & Yang, M. "High Throughput Confined Migration Microfluidic Device for Drug Screening” Small. 2023,19, 16, 2207194 (Front cover)
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Ni, Y., Liu, X., Simeneh, Z. M., Yang, M. & Li, R. "Benchmarking of Nanopore R10.4 and R9.4.1 flow cells in single-cell whole-genome amplification and whole-genome shotgun sequencing”, Computational and Structural Biotechnology Journal. 2023, 21, p. 2352-2364 13 p.
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Yang, Z., Zhou, L., Si, T., Chen, S., Liu, C., Ng, K. K., Wang, Z., Chen, Z., Qiu, C., Liu, G., Wang, Q., Zhou, X., Zhang, L., Yao, Z., He, S., Yang, M. & Zhou, Z. “Lysyl hydroxylase LH1 promotes confined migration and metastasis of cancer cells by stabilizing Septin2 to enhance actin network” Molecular Cancer. 2023, 22, 21
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Li, W., Zhou, Z., Zhou, X., Khoo, B. L., Gunawan, R., Chin, Y. R., Zhang, L., Yi, C., Guan, X. & Yang, M. "3D Biomimetic Models to Reconstitute Tumor Microenvironment In Vitro: Spheroids, Organoids, and Tumor-on-a-Chip”, Advanced Healthcare Materials, 2023, .12, 18, 2202609. (Inside Front cover)
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Zhou, Z., Yang, Z., Zhou, L., Yang, M. & He, S., “The versatile roles of testrapanins in cancer from intracellular signaling to cell-cell communication: cell membrane proteins without ligands” Cell & Bioscience. 2023, 13, 59.
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Gunawan, R., Yang, M. & Lau, C., “X-ray measurement of intracellular chloride and other ions in mammalian cells” , Talanta Open. 2023, 7, 100189.
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Ilyas, A. O., Musah, J., Ahmed, R., Gunawan, R., Ahmed, I., Oo, S. L., Venkatesh, S., Yeung, C., Yang, M. & Lau, C. "Intracellular and extracellular ion variation measurement in alpha(α)-particle irradiated cells using t-FROZEN! and laser-induced breakdown spectroscopy”, Results in Optics. 2023, 11, 100388.
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Xia, S., Pan, J., Dai, D., Dai, Z., Yang, M. & Yi, C. Design of portable electrochemiluminescence sensing systems for point-of-care-testing applications, Chinese Chemical Letters. 2023, 34, 5, 107799
2022
Zou H, Yang Z,Chan YS, Yeung SA, Alam MK, Si T, Xu T, Yang M S. Single cell analysis of mechanical properties and EMT-related gene expression profiles in cancer fingers. Iscience, 2022, 103917.
Song Z, Lian S, Mak S, Chow M Z Y, Xu C, Wang W, Keung HY, Lu C, Kebede F T, Gao Y, Cheuk W, Cho W C S, Yang M S, Zheng Z L. Deep RNA sequencing revealed fusion junctional heterogeneity may predict crizotinib treatment efficacy in ALK-rearranged NSCLC. Journal of Thoracic Oncology, 2022, 17 (2), 264-276.
Kan T, Zhang S, Zhou S, Zhang Y, Zhao Y, Gao Y, Zhang T, Gao F, Wang X, Zhao L, Yang M S. Single-cell RNA-seq recognized the initiator of epithelial ovarian cancer recurrence. Oncogene, 2022, 1-12.
Liu Y, Xiao M, Xu N, Yang M S. Point-of-need quantitation of 2,4-dichlorophenoxyacetic acid using a ratiometric fluorescent nanoprobe and a smartphone-based sensing system. Sensors and Actuators B: Chemical, 2022: 132083.
Cui, M., Chen, X., Luo, X., Zhou, Z., Chen, Z., Zhou, Z., ... & Yang, M. Dually stimulative single-chain polymeric nano lock with dynamic ligands for sensitive detection of circulating tumor cells. Biosensors and Bioelectronics, 217, 114692.
Wang Q, Yang Q, Liu C, Wang G, Song H, Shang G, Peng R, Qu X, Liu S, Cui Y, Wang P, Xu W, Zhao X, Qi J, Yang M, Gao GF. Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4): e2118590119.
2021
Editors: Mengsu (Michael) Yang, Michael Thompson. Detection Methods in Precision Medicine. Publisher: Royal Society of Chemistry 2021. https://pubs.rsc.org/en/content/ebook/978-1-78801-761-9.
Chen Y, Zhou X, Yang M S. Nanopore Sequencing and Detection of Tumor Mutations. / Detection Methods in Precision Medicine. ed. / Mengsu Yang; Michael Thompson. Royal Society of Chemistry, 2021, 137-152
Li H, Liu P, Gunawan R, Simeneh Z M, Liang C, Yao X, Yang M S*. Magnetothermal Miniature Reactors Based on Fe3O4 Nanocube-Coated Liquid Marbles. Advanced Healthcare Materials, 2021, 10 (6), 2001658.
Ilyas A M, Alam M K, Musah J, Yang M S, Vellaisamy A L R, Lam Y W, Lau C. CHO cell dysfunction due to radiation-induced bystander signals observed by real-time electrical impedance measurement. Biosensors and Bioelectronics, 2021, 181, 113142.
Ilyas A, Alam M K, Musah J, SAW L O, Venkatesh S, Yeung C, Yang M S, Vellaisamy A L R, Lau C. Development of a carboxyl-terminated Indium Tin Oxide electrode for improving cell adhesion and facilitating low noise, real-time impedance measurements. American Journal of Physiology - Cell Physiology, 2021, 320 (6), 974-986.
Horowitz L F, Rodriguez A D, Au-Yeung A, Bishop K W, Barner L A, Mishra G, Raman A, Delgado P, Liu J T C, Gujral T S, Mehrabi M, Yang M S, Pierce R H, Folch A. Microdissected “cuboids” for microfluidic drug testing of intact tissues. Lab on a Chip, 2021, 21(1), 122-142.
Ye Z, Wang D, Zhang L, Yang M S, Yue J, Lu Y, He Y, Yu J, Wei W, Chen C, Wang R, Zhang L, Le M, Cho W C, Zhang H. Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ. Oncogene, 2021, 40 (10), 1775–1791.
Ilyas A M O, Alam M K, Musah J D, Yang M S, Lam Y, Roy V A L, Lau C. Investigation on the Direct and Bystander Effects in HeLa Cells Exposed to Very Low α-Radiation Using Electrical Impedance Measurement. ACS Omega, 2021, 6 (22), 13995–14003.
Lai X, Geng X, Li M, Tang M, Liu Q, Yang M S, Shen L, Zhu Y, Wang S. Glutathione-responsive PLGA nanocomplex for dual delivery of doxorubicin and curcumin to overcome tumor multidrug resistance. Nanomedicine, 2021, 16 (16), 1411–1427.
Gunawan R, Imran A, Ahmed I, Liu Y, Chu Y, Guo L, Yang M S, Lau C. FROZEN! Intracellular multi-electrolyte analysis measures millimolar lithium in mammalian cells. Analyst, 2021, 146 (16), 5186–5197.
Chen Y, Wu T, Zhu Z, Huang H, Zhang L, Goel A, Yang M S, Wang X. An integrated workflow for biomarker development using microRNAs in extracellular vesicles for cancer precision medicine. Seminars in Cancer Biology, 2021, 74, 134-155.
Song Z, Lian S, Mak S, Chow M, Xu C, Wang W, Keung H, Lu C, Kebede F T, Gao Y, Cheuk W, Cho W C S, Yang M S, Zheng Z. Deep RNA Sequencing Revealed Fusion Junctional Heterogeneity May Predict Crizotinib Treatment Efficacy in ALK-Rearranged NSCLC. Journal of Thoracic Oncology, 2021.
Han P, Su C, Zhang Y, Bai C, Zheng A, Qiao C, Wang Q, Niu S, Chen Q, Zhang Y, Li W, Liao H, Li J, Zhang Z, Cho H, Yang M S, Rong X, Hu Y, Huang N, Yan J, Wang Q, Zhao X, Gao F, Qi J. Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nature Communications, 2021, 12 (1), 6103.
2020
Ni Y, Cui Y, Zou H, Xu T, Yang M S. Single-cell Sequencing of Circulating Tumor Cells: Recent Technical Advances, Challenges and Applications. Detection Methods in Precision Medicine. 2020, 169-190.
Chen Y, Zhou X, Yang M S. Nanopore sequencing and detection of tumor mutations. Detection Methods in Precision Medicine. 2020, 18, 137.
Li T Z, Huang L F*, Yang M S.* “Lipid-based vehicles for siRNA delivery in biomedical field”, Current Pharmaceutical Biotechnology, 2020, 21(1), 3-22.
Liu D D, Hong Y C, Li Y P, Hu C, Yip T C, Yu W K, Zhu Y, Fong C C, Wang W M, Au S K, Wang S B, Yang M S.* “Targeted destruction of cancer stem cells using multifunctional magnetic nanoparticles that enable combined hyperthermia and chemotherapy”, Theranostics 2020, 10(3), 1181-1196.
Rashid A, Duan X, Gao F, Yang M S,* Yen A.* "Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signalling molecules and augments ATRA-induced myeloid cell differentiation", Oncotarget, 2020, 11, 1017-1036.
Xiao M, Liu Z G, Xu N X, Jiang L L, Yang M S, Yi C Q.* “A smartphone-based sensing system for on-site quantitation of multiple heavy metal ions using fluorescent carbon nanodots-based microarrays”, ACS Sensors, 2020, 5, 870-878.
Rashid A, Duan X, Gao F, Yang M S,* Yen A.* “Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: novel effects on signalling molecules for a putative Cdk2 inhibitor”, Cellular Signalling, 2020, 71, 109555.
Kan T T, Wang W, Ip P P, Zhou S T, Wong A S, Wang X, Yang M S.* “Single-cell EMT-related transcriptional analysis uncovers the intra-cluster heterogeneity of tumor cell clusters in epithelial ovarian cancer ascites”, Oncogene, 2020, 39(21), 4227–4240.
Liang C, Zhang X L, Wang Z C, Wang W J, Yang M S*, Dong X C.* “Organic/Inorganic nanohybrids rejuvenate photodynamic cancer therapy”, Journal of Materials Chemistry B, 2020, 8(22), 4748-4763.
Rashid1 A, Wang R, Zhang L, Yue J B, Yang M S,* Yen A.* “Dissecting the novel partners of nuclear c-Raf and its role in all-trans retinoic acid (ATRA)-induced myeloblastic leukemia cells differentiation”, Experimental Cell Research, 2020, 111989.
Zhang W X, Li S C, Li X P, Liu M, Cui T Y, Fu H Y, Yang M S, Zhong W Y, Xu B, Yue W Q.* “PEG-PtS2 nanosheet-based fluorescence biosensor for label-free human papillomavirus genotyping”, Microchimica Acta, 2020, 187(7), 408 -415.
Liang C, Zhang X L, Cheng Z J, Yang M S*, Huang W, Dong X C.* Magnetic iron oxide nanomaterials: A key player in cancer nanomedicine, VIEW, 2020, 20200046.
Feng L, Xie Y S, Au-Yeung S K, Hagos B H, Liu Z Y, Chen Q X, Zhang J, Pang, Q X, Yao X, Yang M S, Zhang L,* Sun H Y.* A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells, Chemical Communications, 2020, 56, 8480-8483.
Li X P, Cui T Y, Zhang W X, Zhai Z R, Wu F X, Zhang Y W, Yang M S, Zhong W Y, Yue W Q.* “Dopamine-functionalized hyaluronic acid microspheres for effective capture of CD44-overexpressing circulating tumor cells”, Colloids and Surfaces B: Biointerfaces, 2020, 196, 111281-111288.
Thakur A, Sidu R K, Zou H, Alam M K, Yang M S, Lee Y J.* Inhibition of glioma cells’ proliferation by doxorubicin-loaded exosomes via microfluidics, International Journal of Nanomedicine, 2020,15: 8331–8343.
Liang C, Zhang X, Yang M S, Wang W, Chen P, Dong X. Remodeling tumor microenvironment by multifunctional nanoassemblies for enhanced photodynamic cancer therapy. ACS Materials Letters, 2020, 2 (10), 1268-1286.
Zhang X, Liang C, Qu X, Ren Y, Yin J, Wang W, Yang M S, Huang W, Dong X C. Sandwich‐Structured Fe‐Ni2P/MoSx/NF Bifunctional Electrocatalyst for Overall Water Splitting. Advanced Materials Interfaces. 2020, 7 (12), 19019.
2019
Xu T, Fu H Y, Li YP, Chen X M, Cheuk W, Li C W, Zou H, Yue W Q, Au S K, Wang Y, Yang M S.* Single cell target gene mutation analysis by arc-edge-channel monolithic valve microfluidic cell isolation and locked nucleic acid based PCR detection. Sensors and Actuators B: Chemical, 2019, 293, 224-234.
Li T Z, Yang M S.* Vesicle trafficking, autophagy and nanoparticles: a brief review. Current Nanomedicine, 2019, 9, 1-17.
Liang C, Zhang X L, Yang M S*, Dong X C.* Recent progress of ferroptosis iducers for cancer therapy. Advanced Materials, 2019, 1904197.
Li C, Li T, Huang L, Yang M S, Zhu G. Self‐assembled Lipid Nanoparticles for Ratiometric Codelivery of Cisplatin and siRNA Targeting XPF to Combat Drug Resistance in Lung Cancer. Chemistry–An Asian Journal, 2019, 14 (9), 1570-1576.
Li T, Yue J, Huang L, Yang M S. Autophagy inhibitor Vacuolin-1 interferes with lipid-based small interference RNA delivery. Biochemical and biophysical research communications, 2019, 510 (3), 427-434.
2018
Alam MK, Koomson E, Zou H, Yi C, Li C W, Xu T, Yang M S. Recent advances in microfluidic technology for manipulation and analysis of biological cells (2007–2017). Analytica chimica acta, 2018, 1044, 29-65.
Li Y, Yu W K, Chen L, Liu D, Fong C C, Xu T, Zhu G, Sun D, Yang M S. Electrotaxis of tumor-initiating cells of H1975 lung adenocarcinoma cells is associated with both activation of stretch-activated cation channels (SACCs) and internal calcium release. Bioelectrochemistry, 2018, 124, 80-92.
Zhu S, Li H, Yang M S, Pang S W. Label-free detection of live cancer cells and DNA hybridization using 3D multilayered plasmonic biosensor. Nanotechnology, 2018, 29 (36), 365503.
Wang W, Liu D, Liang C, Yu W K, Zou H, Kan T, Chan Y S, Fong C C, Yang M S. Development of nanomedicine targeting cancer stem cell. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14 (5), 1875.
Thakur A, Zou H, Yang M S, Lee Y. Augmented loading efficiency of doxorubicin into glioma-derived exosomes by an integrated microfluidic device. Cancer Research, 2018, 78, 3720-3720.
Yu W K, Chan Y S, Wang W, Fong C, Yip T C, Au S K, Yang M S. Dynamic interconversion between CD90+ and CD90− cancer cell populations in lung cancer A549 cell line. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14 (5), 1822.
Li H, Liu P, Zou H, Li Y, Yao X, Yang M S. Development of transparent and gas-permeable liquid marbles for culture and drug sensitivity test of tumor cell spheroids. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14 (5), 1784.
K T, Lan Z, Xin W, Wong A S T, Y M S. Single-cell analysis of EMT-related gene expression heterogeneity in metastatic tumor cell clusters isolated from ovarian cancer ascites. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14 (5), 1782.
Chan Y S, Yu E W K, Wang W W, Fong C C, Yip T T C, Au J S K, Yang M S. Single-cell analysis of population-based phenotypic switching of cancer cells. Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14 (5), 1806.
Usman W M, Pham T C, Kwok Y Y, Vu L T, Ma V, Peng B, Chan Y S, Wei L, Chin S M, Azas A, He A B L, Leung A Y H, Yang M S, Chang N S, Cho W C, Shi J H, Le M T N. Efficient RNA drug delivery using red blood cell extracellular vesicles. Nature communications, 2018, 9 (1), 1-15.
Pan Y, Chen W, Yang J, Zheng J, Yang M S, Yi C. Facile synthesis of gadolinium chelate-conjugated polymer nanoparticles for fluorescence/magnetic resonance dual-modal imaging. Analytical chemistry, 2018, 90 (3), 1992-2000.
Zhu S, Li H, Yang M S, Pang S W. Highly sensitive detection of exosomes by 3D plasmonic photonic crystal biosensor. Nanoscale, 2018, 10 (42), 19927-19936.
2017
Li H, Liu P, Kaur G, Yao X, Yang M S. Liquid Marbles: Transparent and Gas‐Permeable Liquid Marbles for Culturing and Drug Sensitivity Test of Tumor Spheroids. Advanced healthcare materials, 2017, 6 (13), 1700185 (1-6).
Li Y, Xu T, Zou H, Chen X, Sun D, Yang M S. Cell migration microfluidics for electrotaxis-based heterogeneity study of lung cancer cells. Biosensors and Bioelectronics, 2017, 89, 837-845.
Li Y, Xu T, Chen X, Lin S, Cho M, Sun D, Yang M S. Effects of direct current electric fields on lung cancer cell electrotaxis in a PMMA-based microfluidic device. Analytical and bioanalytical chemistry, 2017, 409 (8), 2163-2178.
Yu W K, Wang Z, Fong C C, Liu D, Yip T C, Au S K, Zhu G, Yang M S. Chemoresistant lung cancer stem cells display high DNA repair capability to remove cisplatin‐induced DNA damage. British journal of pharmacology, 2017, 174 (4), 302-313.
Su L, Fong C C, Cheung P Y, Yang M S. Development of novel piezoelectric biosensor using pzt ceramic resonator for detection of cancer markers. Biosensors and biodetection, 2017, 277-291.
Patents
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Yang, M. S., Ayele, B. W., Gunawan, R., Wu, W. Q., 用於實時側流測定的一鍋式病原體檢測系統和方法, PRC Patent application No. 202310704339.9. Filed on Jun 14, 2023.
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Xiao, X. J., Yang, M. S., Zhou, X. Y., Mu, Y. Q., Wang, Y. “Automatic high-throughput and non-invasive selection of single sperm atbiochemical level”. US Patent application No. 63/498,524. Filed on Apr 27, 2023.
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Yang, M. S., Ayele, B. W., Gunawan, R., Wu, W. Q., “One-pot pathogen detection system and method for real-time lateral flow assay”. US Patent application No. 18/188,527. Filed on Mar 23, 2023.
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Yang, M. S., Wang, Y., Zhou, X. Y. “Hydrogel-based cell encapsulation method, a cell or cell-encapsulating polymerized microgel and a system thereof, and kit thereof”. PCT Patent application No. PCT/CN2023/095763. Filed on Mar 23, 2023.
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Yang, M. S., Liang, P. B., 用于捕获短游离DNA的微流控装置及其制备方法, PRC Patent application No. 202211729504.8. Filed on Dec 30, 2022.
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Yang, M. S., Wang, Z. S Zheng, S., Li, W. X., Si, T. X., Zhou, X. Y,, Fang, Z. J., Hou, X. H..用于分离外泌体的纳米材料及其制备方法、应用 PRC Patent application No. 2022114722900. Filed on Nov 23, 2022.
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Yang, M. S., Yang, Z. H.,Zhou, Z. H., Mitochornic acid 5在治疗肿瘤中的应用PRC Patent application No. 202211209606.7. Filed on Sep 30, 2022.
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Yang, M. S., Yang, Z. H.,Zhou, Z. H., 一种与肿瘤治疗相关的药物PRC Patent application No. 202211209611.8. Filed on Sep 30, 2022.
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Yang, M. S., Ayele, B. W., Gunawan, R. 用於核酸分子即時測試檢測的樣品進結果出封閉式微流控裝置 PRC Patent application No. 202211115598.X. Filed on Sep 14, 2022.
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Yang, M. S., Yang, Z. H.,Zhou, Z. H., Si, T. X., Zhou, Z. D., “Confined migration microfluidic device for cell culture and drug screening”. US Patent application No. 17/822,209. Filed on Aug 25, 2022.
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Yang, M. S., Ayele, B. W., Gunawan, R. “Sample-in-result-out closed microfluidic module for nucleic acid molecular POCT detection”. US Patent application No. 17/816,769. Filed on Aug 2, 2022.
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Yang, M. S., Wang, Y., Zhou, X. Y. 細胞凍存保護組合物,體系,方法及應用. PRC Patent application No. 202210604660.5; filed on May 30, 2022.
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Yang, M. S., Zhou, X. Y, Wang, Y., Hou, X. H. .基於水凝膠的細胞包裹方法、細胞或包裹有細胞的水凝膠顆粒及其體系、其用途及試劑盒PRC Patent application No. 202210600576.6; filed on May 30, 2022.
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Yang, M. S.; Xu T., Zou H. 弧形邊緣截面的PDMS母模、微流控閥和芯片及其製備。PRC Patent application No. ZL201911225005.3; filed on May 30, 2022. Granted.
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YANG, M., YANG, Z., ZHOU, Z., SI, T., & ZHOU, Z., inventors, Microfluidic device targeting on confine cell migration and drug screening. May 2022, Priority No. 202210557883.0
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YANG, M., CUI, M., YANG, Z., ZHOU, X., ZHOU, Z. & HOU, X., inventors, A novel integrated microfluidic chip for highly efficient and high throughput in vitro culture of circulating tumor cells (CTCs) for drug screening. 20 Apr 2022, Priority No. 202210414895.8
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YANG M, CUI M, LI W, LI D, ZHOU X, inventors. Development of an integrated microfluidic device for simulating tumor microenvironment and high-throughput anti-cancer drug screening. 2022 Apr 12.
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Yang M S, AYELE B W, Gunawan R, Ng K K, Au-Yeung A S K. 一種檢測裝置及檢測方法. 2021, Priority No. 202110366006.0
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Yang M S, Liu D. Nanoparticle Composition for use in Targeting Cancer Stem Cells and Method for Treatment of Cancer. 2020, Patent No. US 10682421, Priority No. 15/915,166.
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Yang M S, Xu T, Zou H. 用於基因突變檢測的發夾式擴增阻斷法的引物和探針及其應用. 2019, Priority No. 201911392622.2
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Yang M S, Xu T, Zou H. 一種基於層流擴散的血液中外泌體富集微流控芯片. 2019, Priority No. 201911299368.1
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Yang M S, Xu T, Zou H. 弧形邊緣截面的PDMS母模、微流控閥和芯片及其製備. 2019, Priority No. 201911225005.3
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Yang M S, Xu T, Zou H. 一種微流控芯片. 2019, Priority No. 201911165210.5
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Yang M S, Liu D D. Nanoparticle Composition for Use in Targeting Cancer Stem Cells and Method for Treatment of Cancer. 2017, Priority No. 17102497.5
Grants
Prof. M. Yang (PI), “Development of Anti-cancer Therapy with Externally Activated Nanomedicine”, Innovation and Technology Fund (ITS), Project Number: ITS/100/14FP, 03/2015-12/2017, 2,400,000 HKD.
Prof. M. Yang (PI), “Quantitative study of cancer stem cells growth, migration and communication with cancer cells in a microfluidic-based biomimetic microenvironment”, General Research Grant, Project Number: (CityU_11303815), 09/2015-08/2018, 706,972 HKD.
Prof. M. Yang (PI), “Development of an integrated microfluidic-based system for single cell mutation analysis and drug sensitivity test of circulating tumor cells/cell clusters”, General Research Grant, Project Number: (CityU_11319516), 09/2016-08/2019, 540,824HKD.
Prof. M. Yang (PI), “Development of microfluidic technology for detection and characterization of circulating tumor cells and cell clusters”, Guangdong Key Research and Innovation Grant, Project Number: (CityU_9680217), 09/2017-08/2019, 3,000,000 RMB.
Prof. M. Yang (PI), “Development of Rapid Test Kit for SARS-Cov2”, Innovation and Technology Fund (PTPS), Project Number: ITS/100/14FP, 06/2020-2/2021, 1,400,000 HKD.
Prof. M. Yang (PI), “Development of an integrated microfluidics system for multi-level high content screening of anti-tumor drugs”, Research Impact Fund, Project Number: (CityU_8790001) , 07/2019-06/2022, 9,000,000 HKD.
Prof. M. Yang (PI), “Development and Pre-clinical Study of Externally Activated Nanomedicine for Anti-Cancer Therapy”, Innovation and Technology Fund, Project Number: (MRP/045/21X) , 03/2022-02/2025, 7,337,000 HKD.